منابع مشابه
Macrophage Deactivation by Interleukln 10
Recombinant mouse interleukin 10 (IL-10) was exceedingly potent at suppressing the ability of mouse peritoneal macrophages (mOb) to release tumor necrosis factor a (TNF-o~). The ICs0 of IL-10 for the suppression of TNF-ol release induced by 0.5 #g/ml lipopolysaccharide was 0.04 _+ 0.03 U/ml, with as little as 1 U/ml suppressing TNF-ot production by a factor of 21.4 + 2.5. At 10 U/ml, II.-10 mar...
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Pretreatment of lignocellulosic materials may result in the release of inhibitors and deactivators of cellulose enzyme hydrolysis. We report the identification of phenols with major inhibition and/or deactivation effect on enzymes used for conversion of cellulose to ethanol. The inhibition effects were measured by combining the inhibitors (phenols) with enzyme and substrate immediately at the b...
متن کاملMacrophage deactivation by interleukin 10
Recombinant mouse interleukin 10 (IL-10) was exceedingly potent at suppressing the ability of mouse peritoneal macrophages (m phi) to release tumor necrosis factor alpha (TNF-alpha). The IC50 of IL-10 for the suppression of TNF-alpha release induced by 0.5 microgram/ml lipopolysaccharide was 0.04 +/- 0.03 U/ml, with as little as 1 U/ml suppressing TNF-alpha production by a factor of 21.4 +/- 2....
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evant antigen. These data suggest a model in which populations of tissue-specifi c Tregs arise during thymic development and then accumulate within those peripheral tissues on the basis of antigen recognition (see the fi gure). As tumors develop, these preexisting tissue-resident Tregs are recruited into and/or expanded within the tumor microenvironment, potentially allowing them to exert local...
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Let G = (V, E) be a graph and let N(v) = {u : uv ∈ E} be the open neighborhood of a vertex v ∈ V . The degree of v, deg(v) = |N(v)|, equals the number of vertices u that are adjacent to v. By considering the relationships between deg(v) and the degrees deg(u), for every u ∈ N(v), we define 10 types of vertices and study some of their properties.
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ژورنال
عنوان ژورنال: Science
سال: 2002
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.297.5584.1095a